For each reaction, decide whether substitution or elimination (or both) is possible, and predict the products you expect Part A Draw the major product from the following reaction 1bromo1methylcyclohexane in acetone Draw the molecule on the canvas by choosing buttons from the Tools (for bonds and charges), Atoms, and Templates toolbars Re E1 elimination of 1bromo1methylcylclohexane using KOtBu?The substituents present at 1 and 2 positions of a chair cyclohexane take an axial and an equatorial position in cis form, but both equatorial positions or both axial positions in the trans form Hence, the axial B r has an adjacent axial hydrogen at C 2 and (C 6) in cis form but only at C6 in trans Therefore, the former can give the more substituted 1 but the latter cannot

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1-bromo-1-methylcyclohexane elimination
1-bromo-1-methylcyclohexane elimination-1bromo1methylcyclopentane in methanol as solvent Show all steps and all intermediates involved Use electronpushing arrows to indicate electron flow for each step Show both substitution and elimination productsExplain your answer 5) Provide the structure of the major organic product from the following reaction Br H3C Br KI 6) When 1iodo1methylcyclohexane is treated with NaOCH2CH3 as the base, the more



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QUESTION 6 10 marks) When 1bromo1methylcyclohexane is treated with sodium ethoxide elimination occurs via an E2 mechanism to give a mixture of two alkenes, A and B Br O Na (a) Draw the structures of alkenes A and B (2 marks) Two Elimination Reaction Patterns Master Anic Chemistry Cis1bromo2methylcyclohexane with KOH in ethanol to form 1methylcyclohexene Topic Draw the expected major elimination product and identify the mechanism4) Which diastereomer of 1bromo4tbutylcyclohexane, the cis or the trans, undergoes elimination more rapidly when treated with sodium ethoxide?
NIST/TRC Web Thermo Tables (WTT) NIST Standard Reference Subscription Database 3 Professional Edition Version 2121Pro This web application provides access to a collection of critically evaluated thermodynamic property data for pure compounds with a primary focus on organics These data were generated through dynamic data analysis, as implemented in the NISTIn the presence of a base, an E2 mechanism occurs, where the base attacks a beta hydrogen and removes it and the leaving group to form a pi bond




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